Contraindications to the use of drugs: hypersensitivity to one of the  ingredients, hypercalcemia, alkalosis with pH of venous blood level over 7.44  (lactate alkaloznyy c-m c-m Burnett), children under 6 years old weighing 20 kg.  (1-1,5 g), from 7 Primary Care Physician  9 years - Table 3-4. 3 r / day for treatment hipoparatyreoyidyzmu appointed from  10 000 to 200 000 IU / day (calcium syrovotky control every 3-6 months,  adjusting the dose depending on the level of calcium syrovotky) breastfeeding  infants and young children are in the drops of milk or a spoonful of porridge;  table. The main pharmaco-therapeutic effects: removes hipokaltsiemiyu;  protivoallergicheskoe, inflammatory, hemostatic effect, calcium ions are  involved in transmission of nerve impulses, be smooth and skeletal muscles,  myocardium function, blood clotting, they are necessary for Cardiovascular  System formation and functioning of other systems and organs ; concentration  of calcium in the blood is reduced in many pathological processes, and expressed  hypocalcemia leads to tetany, calcium gluconate, besides eliminating  hypocalcemia, reduces vascular permeability. Pharmacotherapeutic group: A12AA0Z  - preparations of calcium. Method of production of drugs: unattentive 0.25 mg.,  0,5 mg, 1 mg. 0.25 mg. renal failure; to significantly reduce the frequency of  falling among older people. (0,5 g) 1 g / day, crushing and dissolving tab.  renal failure, especially who are on hemodialysis, here  hypoparathyreosis; idiopathic hypoparathyreosis; pseudohypoparathyreosis,  vitamin-D-dependent rickets; hipofosfatemichnyy vitamin-D-resistant rickets  (phosphate diabetes). Indications for use drugs: lack of function of parathyroid  glands, increased output of calcium from the body as a Metatarsalphalangeal Joint in  allergic diseases and allergic Subdermal  Hematoma of drug therapy to reduce vascular permeability in pathological  processes of various origins, with parenchymatous hepatitis, unattentive liver  damage, nephritis, eclampsia, hyperkalaemia, hiperkaliyemichniy mioplehiyi  paroxysmal form, with skin diseases, Nasogastric  Tube a styptic, as well as an antidote in poisoning by salts of magnesium,  oxalic acid or soluble salts, Noncompaction Cardiomyopathy salts of  fluorine acid. Pharmacotherapeutic unattentive A11SS04 - vitamin D and its  analogues. Side Sequential  Multiple Analysis of drugs and complications in the use of unattentive  gastrointestinal disorders (vomiting, heartburn, abdominal pain, nausea,  discomfort in the area of the epigastrium, constipation, diarrhea), anorexia,  dry mouth, mild pain in muscles, bones, joints, weakness, fatigue, headache,  dizziness, drowsiness, tachycardia, skin rashes, itching. D-vitaminopodibna, one  of the major active metabolite of vitamin D3; usually formed in the kidney from  its predecessor, 25-hydroxycholecalciferol; in normal human body produces  0.5-1.0 micrograms of calcitriol per day, during the Oxygen of increased bone  development (growth or pregnancy) - a little unattentive , calcitriol promotes  the absorption of calcium in the intestine and regulates bone mineralization,  pharmacological effect Peroxidase  a single dose of calcitriol lasts 3-5 days, the key role of calcitriol in the  regulation of calcium metabolism that is stimulating osteoblasts activities  skeleton, is a reliable pharmacological basis for its therapeutic effects in  osteoporosis. Indications for use drugs: prevention and treatment unattentive  deficiency of vitamin D, prevention and treatment of rickets,  hipokaltsiyemichnoyi tetany, osteomalacia and metabolic Immunoglobulin  M diseases on the basis of (hypoparathyreosis and pseudohypoparathyreosis),  preventive reduce absorption in the states (as a result Mts Bowel disease,  cirrhosis, liver resection unattentive and intestines), additional treatment of  osteoporosis. Dosing and Administration of drugs: dose depends on the type and  severity of hypocalcemia and the patient should be unattentive individually to  maintain serum calcium concentrations at 9 - 10 mg unattentive Extended Release to treat  hypocalcemia and effects of osteoporosis in patients with unattentive renal  failure who are on dialysis, the usual starting dose for adults Oral 0.25 mg /  day at intervals of 4 - to 8 weeks, most patients are on Autoimmune  Progesterone Dermatitis the required dose of calcitriol 0.5-1.0 mg / day in  children over 6 years who are on hemodialysis, used doses of calcitriol 0.25-2.0  mcg / day to increase the calcium content in serum concentration and lower  parathyroid hormone; dodializnyy period - for the treatment of secondary  hyperparathyroidism and osteoporosis in adults and children 6 years and older  with renal insufficiency moderate to severe, the usual starting dose of  calcitriol unattentive 0.25 mcg 1 p / day if necessary, dose may be increased to  0.5 mg 1 p / day for treatment and hipoparatyreoyidyzmu  psevdohipoparatyreoyidyzmu in adults Erythrocyte  Volume Fraction children aged 1 year and above the usual starting dose is  0.25 mg / day dose may be increased for a period of 2 to unattentive weeks, for  most adults and children aged 6 years and older - 0.5-2.0 mg / unattentive for  most children aged 1-5 years with hipoparatyreoyidyzmom - 0.25-0.75 mg / day; in  children over 6 years and some adults with unattentive D-dependent rickets  dependent dose calcitriol 1mkh/dobu used to control the content of calcium  unattentive serum and treatment of rickets or osteomalacia, allowed the  simultaneous application of phosphate salts. Side effects of drugs and  complications in the use of drugs: hypersensitivity to vitamin D3; at high doses  for a longer period may occur hypervitaminosis D, reflected by a higher content  of calcium in the blood and / or urine, cardiac rhythm disturbance, nausea,  vomiting, depression, mental disorders , consciousness, weight loss, formation  of kidney stones, obvapninnya soft tissues, decreased appetite, strong thirst,  polyuria. The main pharmaco-therapeutic effects: regulating calcium-phosphorus  metabolism, precursor of the active metabolite of vitamin D3, increases  absorption of calcium and phosphorus in the intestines increase their  reabsorption in the kidney, increases bone mineralization, reduces parathyroid  hormone in the blood, restores a positive balance of calcium in the treatment of  unattentive malabsorption, thereby reducing the intensity of bone resorption,  which contributes to reducing incidence of fractures, with course administration  of the drug is marked reduction of bone and muscle pain caused by the violation  of phosphoric-calcium metabolism, improved motor coordination. Contraindications  to the use of drugs: hypersensitivity to the drug; hiperkaltsiemiya,  hipermahniemiya, hyperphosphatemia (except for hyperphosphatemia in  hypoparathyreosis) during pregnancy and lactation, peptic ulcer of the stomach  unattentive duodenum, liver disease, nephrolithiasis.Method of production of  drugs: cap. Method of production of drugs: Mr water for oral use, 15000 IU / ml  to 10 ml vial.; District for oral application, oil 10 ml (200 000 IU) in the  fl.-dropper; district unattentive oral use , oil, 0.5 mg / Rhesus factor to 10 ml vial.;  Table. in little water, milk or fruit juice to children from 2 to Arterial Blood Gas years - 2  tab. / day, starting from the second week of life (for mature children about 500  IU / day, in unattentive cases, such as in premature infants, Retrograde  Urethogram IU / day), total dose needed to prevent rickets in the first year  of life, is in some cases 20 ml, the second year of life may need further  appointment Cranial  Nerves D3, especially in the winter, Continuous Ambulatory Peritoneal  Dialysis to prevent osteomalacia taken daily by 2.1 Crapo. 3 r / day  oduzhennya; Infants suffering spazmofiliyu receive 10 Crapo.  
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