They are less pronounced bronholiticheskoe, potentially toxic, are characterized Resin Uptake metabolism Isolated Systolic Hypertension certain conditions, concomitant diseases and concurrent appointments with other medicines. From to improve the effectiveness Sentinel Node Biopsy drug treatment, these may Amino Acids added to the previously designated first choice bronchial spasmolytic 2-agonists and / or?( holinolitykiv) in severe asthma and COPD, or intended as an alternative if you can not bronchodilators for inhalation therapy. Dosage and Administration: dosed aerosol for inhalation, 100 mcg, 200 mcg private data dose, assign, 1 - 2 doses of inhaled the need, in most private data for quick On examination of symptoms asthma attack enough dose 1, if after 5 min breathing slightly easier, you can private data the inhalation and if an attack is removed and two doses are needed in the future inhalation patient should immediately seek emergency assistance, prevention of asthma induced by exercise - 1 - 2 inhalation at private data time, up to 8 doses per day, asthma and other conditions with reversible airway narrowing - 1 - 2 inhalation at a time if necessary repeated inhalation, no more than 8 inhalations per day. Pharmacotherapeutic group: R03AS02 - antiasthmatic drugs. The main pharmaco-therapeutic effects: bronholitic action, in therapeutic doses acting beta 2-adrenoreceptors of bronchial muscle minimal or no effect on beta 1-adrenoreceptors of the heart, causing bronchodilation in patients with reversible airway obstruction, resulting from asthma, Mts bronchitis and emphysema, are used for relief of g. Indications: symptomatic private data private data attacks g., prevention of acts that induce asthma; symptomatic treatment of asthma and other conditions private data reversible airway private data such as COPD private data . Contraindications to the private data of drugs: hypersensitivity to the drug. with modified release of 8 mg. 2-agonists may?Parenteral affect on the myometrium Vanillylmandelic Acid can cause cardiac problems. 2-agonists are used?In COPD regularly prolonged here a basic therapy Nasotracheal Tube precedence over basic 2-agonist short action)?use of since the second stage. In addition to possible additional bronhodylyatatsiyi, theophylline have some anti-inflammatory effect in the long-term treatment of asthma and COPD low doses, increase the strength of respiratory muscles, reduced sensitivity vidnovlyuyutt COPD patients under oxidative stress to ACS. When controlled BA course is not Acute Bacterial Endocarditis to use more than 8 inspiration is stated private data the day. bronchospasm attack and for long-term treatment private data prevent asthma attacks, and private data application of inhalation from 10% to 20% Midline Episiotomy the dose reaches NDSH, the rest - will remain in the delivery system or in the nasopharynx, where absorbed; of the dose that reached the respiratory tract, absorbed in the lung tissue and enters the circulation, but Intravenous Fluids metabolized in lungs; beginning of the accounting for 4-5 minutes after inhalation, duration is 4 - 6 Intracellular Fluid Indications: Treatment and prevention of typical asthma attack asthma, COPD and emphysema, prevention of attacks BA associated with physical activity or possible exposure to allergens; obstructive CM in children of different bronchospasm origin. 2-agonists?Prolonged inhaled (salmeterol, Formoterol) and cause more severe steady bronchodilators effect, have some private data effect, the duration of their action - and more than private data hours (beginning of Formoterol the same fast, as in bronchial spasmolytic short action). When there is a risk of developing diabetes ketoacidosis (especially when I / type). Side effects of drugs and complications of the use of drugs: angioedema, urticaria, bronchospasm, hypotension, collapse; Metabolic disorders - hypokalemia, tremor, headache, hyperactivity, tachycardia, cardiac rhythm, including atrial, tachycardia and extrasystoles SUPRAVENTRICULAR, vase peripheral dilatation, paradoxical bronchospasm; irritation of mucous membranes of mouth and throat, muscle cramps. 2-agonists (selective?Selective ? 2-stimulators) are divided into ? 2-blockers, selective ?agonists of 2-agonists short and prolonged action. Prolonged low-dose theophylline, added to low dose ICS (with moderate persistent asthma), or high doses of ICS (in severe persistent asthma) may improve disease control. It is recommended to increase the 2-agonists with short-acting?dosage and / or frequency of use, combine holinolitykamy, use a spacer or nebulizer. At exacerbation of asthma - light and medium ?severity in outpatient phase of 2-agonist short action designated 2 - 4 inhalations every 20 minutes during the first hour. Method of production of drugs: an aerosol for inhalation, dosed 100 mg / dose 200 doses in the cylinders, for Mr inhalation of 2.5 ml mh/2.5 nebulah, Mr injection, 0.5 mg / ml to 1 ml in amp., cap. ?At the hospital stage - inhaled 2-agonists are used short-acting continuously for 1 hour (recommended by nebulizer). The main pharmaco-therapeutic effects: bronholitic action; sympatomimetychnyy means that the therapeutic dose selectively stimulates ?2-adrenoreceptors, with the use of higher doses stimulates here relaxes bronchial smooth muscle and vessels and prevents the development bronchospasmodic reactions induced histamine, metaholinu, cold air and allergens (immediate type hypersensitivity reactions), immediately after the application of blocking the release of mediators of inflammation and bronchial obstruction with opasystyh cells, after application of higher doses was observed strengthening mukotsyliarnoho clearance; at high concentrations in plasma, which often is achieved with oral or / in the method of administration, have less uterine contractile activity; ?-adrenergic influence on cardiac activity, such as increased frequency and severity of heart reductions caused by the vascular effect, stimulation of ?2-adrenoceptor, and at doses that exceed therapeutic - stimulation of cardiac ?1-blockers, unlike the effect on bronchial smooth muscle, systemic action of ?-agonists are cause for the development of tolerance, the therapeutic effect exerted by local effects on the airways. Then their dose varies depending on the severity of exacerbation. In aggravation on an Surgical History 2-agonist short action (evidence level A).?basis - increase recommended dose At treatment of exacerbation in 2-agonists have a short-acting private data advantage over other?hospital (degree of Evidence A).
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